150780-67-9

Product Details:

CasNo： 150780-67-9

Molecular Formula： C45H56N7O9P

Appearance： White to light yellow solid

Packing： Bottle

Throughput： 1KG/Month

Purity： 99%

Synonyms: 2'-O-Methy-rG(N-ibu)Phosphoramidite;N-blocked-5'-O-DMT-2'-O-Me CED guanosine phosphoramidite;5'-O-(4,4-Dimethoxytrityl)-2'-O-methyl-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite;5'-O-DMT-2'-O-Me-rG(N-iBu)-3'-CEDPA;2'-OMe-ibu-G Phosphoramidite;5'-O-DMT-2'-O-Me-G(ibu) phosporamidite;DMT-2′O-Methyl-rG(ib) Phosphoramidite;ibu-2'-OMe-G Phosphoramidite

Solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly, Sonicated)

PKa: 9.16±0.20(Predicted)

SMILES:O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,44,47,r|

Uses: 2''-OMe-ibu-G Phosphoramidite (CAS# 150780-67-9) is used in the synthesis of native-like crosslinked duplex RNA via interstrand crosslinking reaction between vinylpurine on one strand and target cytosine or uracil on the opposite strand.

Definition:2'-OMe-ibu-G Phosphoramidite is a chemically unstable and heat-sensitive nucleoside phosphoramidite that serves as a foundational element in oligonucleotide synthesis. 2'-OMe-RNA CE (β-cyanoethyl) Phosphoramidites are designed to produce synthetic oligonucleotides containing nuclease resistant 2'-O-methyl ribonucleotide linkages. Deprotection, isolation and handling of 2'-O-methyl oligonucleotides are identical to the procedures for oligodeoxynucleotides.