154947-66-7
- Product Name：LL-37
- Molecular Formula：C205H340N60O53
- Purity：99%
- Molecular Weight：4493.26
Product Details:
CasNo： 154947-66-7
Molecular Formula： C205H340N60O53
Appearance： White or almost white powder
Delivery Time： Delivery on time
Packing： Bottle
Throughput： 2KG/Month
Purity： 99%
Synonyms：Antibacterial Protein LL-37 (huMan), LL37, CAMP; Antibacterial Protein LL-37 (human); LL-37 (trifluoroacetate salt); Cathelicidin LL 37 (human); LL-37, LL37, CAMP; LL-37 human acetate
Water Solubility：Soluble to 1 mg/ml in water
Sequence：Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser
Uses：
LL-37 is a 37 amino acid host defense peptide originating from the C-terminal of the human cathelicidin antimicrobial peptide (CAMP, hCAP18). This peptide possesses antimicrobial, antitumor, antiviral, and immunomodulatory properties, along with physiological functions in chemotaxis, wound healing, and angiogenesis. Beyond its antimicrobial capabilities, LL-37 influences various pathways in autoimmune and inflammatory diseases, playing a role in the development of lupus, rheumatoid arthritis, and atherosclerosis. As a binding partner to Aβ42, the expression of LL-37 affects the onset and progression of Alzheimer's disease. Additionally, LL-37 has a notable role in human cancer, promoting tumorigenic effects in ovarian, lung, breast, prostate, pancreatic cancers, and malignant melanoma.
Relevant Products
-
ApixabanCAS：503612-47-3
-
Benoxinate HydrochlorideCAS：5987-82-6
-
Isoflurane InhalantCAS：26675-46-7
