1401708-83-5
- Product Name：Dihexa
- Molecular Formula：C27H44N4O5
- Purity：99%
- Molecular Weight：504.66
Product Details:
CasNo： 1401708-83-5
Molecular Formula： C27H44N4O5
Appearance： White or almost white powder
Delivery Time： Delivery on time
Packing： Bottle
Throughput： 2KG/Month
Purity： 99%
Synonyms：N-hexanoic-Try-Ile-(6)-amino hexanoic amide; PNB-0408; Dihexa (PNB-0408); N-(1-OXOHEXYL)-L-TYROSYL-N-(6-AMINO-6-OXOHEXYL)-L-ISOLEUCINAMIDE; L-Isoleucinamide, N-(1-oxohexyl)-L-tyrosyl-N-(6-amino-6-oxohexyl)-
Boiling point: 866.2±65.0 °C
Density: 1.111±0.06 g/cm3
Solubility: DMSO (Slightly), Methanol (Slightly)
Pka: 9.83±0.15
Sequence：Hexanoyl-Tyr-Ile-Ahx-NH2
Description:
Dihexa also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is an oligopeptide drug derived from angiotensin IV that binds with high affinity to hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal models of Alzheimer's disease-like mental impairment. In an assay of neurotrophic activity, Dihexa was found to be seven orders of magnitude more potent than brain-derived neurotrophic factor.
Uses：
Dihexa is an angiotensin IV analog as a procognitive/antidementia agent.
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