251647-55-9

Product Details:

CasNo： 251647-55-9

Molecular Formula： C47H60N7O10P

Appearance： White to off-white Powder

Packing： Bottle

Throughput： 1KG/Month

Purity： 99%

Synonyms: DMT-2μ-O-Me-rG(ib) amidite;5'-O-DMT-N2-isobutyryl-2'-O-methylguanosine 3'-CE phosphoramidite;Guanosine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)-, 3'-[2-cyanoethyl bis(1-Methylethyl)phosphoraMidite];2'-MOE-G(iBu)-3'-phosphoramidite;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-methylguanosine-3'-(2-cyanoethyl diisopropylphosphoramidite);5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite;2'-O-MOE-G(iBu)-CE Phosphoramidite

PKa: 9.16±0.20(Predicted)

InChIKey:LADCDGNEBIQAAU-KEFUZROQNA-N

Description:Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2μ-O-Me-rG(ib) amidite, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.

Uses:5''-O-DMT-N2-isobutyryl-2''-O-(2-methoxyethyl)-guanosine 3''-CE phosphoramidite (CAS# 251647-55-9) is a nucleotide, and a derivative of guanosine, and is used in the stereochemical sythesis of phosphorothioate oligonucleotides.