163759-97-5
- Product Name：DMT-2'-O-MOE-rU Phosphoramidite
- Molecular Formula：C42H53N4O10P
- Purity：99%
- Molecular Weight：804.86
Product Details:
CasNo： 163759-97-5
Molecular Formula： C42H53N4O10P
Appearance： White to off-white Solid
Packing： Bottle
Throughput： 1KG/Month
Purity： 99%
Synonyms: (2R,3R,4R,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)-4-(2-METHOXYETHOXY)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE;5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite];5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite;5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite;2'-O-MOE-U-CE Phosphoramidite;2'-O-MOE-U-3'-phosphoramidite;2'-O-MOE-U Phosphoramidite;Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
PKa: 9.39±0.10(Predicted)
InChIKey:ZLOKLUONKGURQI-LWTSSKLSNA-N
SMILES:O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(=O)NC2=O)[C@H](OCCOC)[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,36,42,r|
Description:2'-O-MOE-U-3'-phosphoramidite (DMT-2'-O-MOE-rU Phosphoramidite) is a 2'-O-MOE-protected nucleoside phosphoramidite that can be inserted into oligonucleotide phosphoramidites for antisense RNA. The 2'-MOE backbone enhances stability, resists nuclease, and exhibits low toxicity for improved genetic manipulation.
Uses:2'-O-MOE-U is a phosphoramidite, can be used for oligonucleotide synthesis[1].
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