151533-22-1

Product Details:

CasNo： 151533-22-1

Molecular Formula： C20H23CaN7O6

Appearance： Off-white to pale yellow solid

Delivery Time： 2 weeks after order

Packing： Aluminium bag

Throughput： 10000KG/Month

Purity： 99%

Calcium L-5-methyltetrahydrofolate, also known as active folic acid, can be directly absorbed and utilized by the human body without metabolic conversion. Its applications span multiple fields including pharmaceuticals, health supplements, food, and specific uses in the chemical industry. Detailed introductions are as follows:

1. Pharmaceutical Field

• Disease Treatment: Used for treating megaloblastic anemia caused by folic acid deficiency; combined with 5-fluorouracil for the treatment of advanced colon and rectal cancer; effective in preventing and managing Alzheimer's disease, and also provides auxiliary improvement for autoimmune diseases such as psoriasis and rheumatoid arthritis.
• Drug Detoxification: A specialized antidote for folate antagonists (e.g., methotrexate, pyrimethamine), it prevents severe toxic reactions caused by methotrexate overdose or high-dose therapy, ensuring medication safety.
• Pharmaceutical Excipient: Serves as a core raw material for formulating various dosage forms such as tablets, capsules, and oral solutions; can also be compounded with other vitamins and minerals to produce multi-component pharmaceutical preparations.

2. Health Supplement and Nutrition Field

As a high-quality folic acid supplement in health products:

• For women planning pregnancy or during pregnancy, it prevents fetal neural tube defects;
• For the general population, it supports cell division and DNA synthesis, maintains normal nervous system function, assists in regulating immunity, and prevents cardiovascular issues such as arteriosclerosis;
• Suitable for nutritional needs of various populations, including those with MTHFR gene mutations.

3. Food Field

Commonly added as a nutritional fortifier to various foods, including modified milk, solid beverages, ready-to-eat cereals (e.g., rolled oats), and fruit/vegetable juice drinks. It is also used in nutritional supplements for pregnant women and lactating mothers, as well as sports nutrition products. The dosage must comply with relevant regulations such as the "National Food Safety Standard for the Use of Food Nutritional Fortifiers" (GB 14880) during addition.

4. Chemical Industry Field

• Analytical Standard: Used as a reference standard in chromatographic analysis (e.g., HPLC) and mass spectrometry (e.g., LC-MS) for calibrating detection instruments and verifying the accuracy of analytical methods;
• Material Modifier: Improves the surface properties of materials such as nanoparticles, ceramics, and plastics through chemical bonding, enhancing dispersion, hydrophilicity, and compatibility with other components;
• Synthetic Intermediate: Participates in the production of compounds such as vitamin D derivatives as an intermediate.