1334237-71-6
- Product Name：Etelcalcetide HCl
- Molecular Formula：C38H74ClN21O10S2
- Purity：99%
- Molecular Weight：1084.71186
Product Details:
CasNo： 1334237-71-6
Molecular Formula： C38H74ClN21O10S2
Appearance： White or almost white powder
Delivery Time： Delivery on time
Packing： Bottle
Throughput： 5KG/Month
Purity： 99%
Synonyms：Etelcalcetide Hydrochloride; Etelcalcetide Hydrochloride (AMG-416); AMG416; KAI-4169; Parsabiv; velcalcetide hydrochloride
Solubility: DMSO: 10.0 (Max Conc. mg/mL); 8.37 (Max Conc. mM)
PBS (pH 7.2): 10.0 (Max Conc. mg/mL); 8.37 (Max Conc. mM)
Water: 50.0 (Max Conc. mg/mL); 41.87 (Max Conc. mM)
Sequence: 9.83±0.15
Sequence: Ac-d-Cys(Cys)-d-Ala-d-Arg-d-Arg-d-Arg-d-Ala-d-Arg-NH2 (Disulfide bridge: Cys-Cys)
Uses：
Etelcalcetide hydrochloride (AMG 416 hydrochloride; KAI-4169 hydrochloride) is a synthetic calcimimetic as an activator of the calcium sensing receptor (CaSR). Etelcalcetide hydrochloride is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis, which is promising for research in the field of secondary hyperparathyroidism and chronic kidney disease.
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