1321816-57-2

Product Details:

CasNo： 1321816-57-2

Molecular Formula： C27H28F3N3O8S

Appearance： White to off-white Powder

Packing： Aluminium bag

Throughput： 100KG/Month

Purity： 99%

Product Description

Generic Name: Linzagolix choline Class: Orally‑active, selective non‑peptide gonadotropin‑releasing hormone (GnRH) receptor antagonistPMC Mechanism of Action: Linzagolix choline competitively binds to GnRH receptors in the anterior pituitary gland, blocks endogenous GnRH signaling, and dose‑dependently suppresses the secretion of luteinizing hormone (LH) and follicle‑stimulating hormone (FSH). This reduces circulating estradiol and progesterone levels to relieve symptoms of estrogen‑dependent gynecologic disorders.

Therapeutic Indications（EMA approved）electronic...

Indicated in adult women of reproductive age:

1. Treatment of moderate‑to‑severe symptoms of uterine fibroids (uterine leiomyoma), including heavy menstrual bleeding, pelvic pain, pressure‑related discomforts and anaemia.
2. Symptomatic treatment of endometriosis in women with a prior history of medical or surgical treatment for endometriosis.

Note: Approved brand name: Yselty®. Oral tablet, once‑daily dosing; may be administered with or without hormonal add‑back therapy to mitigate bone‑mineral‑density loss riskelectronic....

Physicochemical Brief (API)

• Appearance: White to off‑white solid powder
• Salt form: Choline salt (improves aqueous solubility & oral bioavailability)
• Storage: Store at ambient temperature, keep tightly sealed, protect from moisture.